I have often seen patients with chronic kidney disease who have an abnormal serum protein electrophoresis (SPEP) or free light chain (FLC) ratio and are referred to hematology before a nephrology evaluation. Many undergo an extensive hematologic workup, including a bone marrow biopsy, before their kidney disease is assessed. If the biopsy is negative for multiple myeloma or other hematologic malignancy, the abnormal monoclonal studies are attributed to monoclonal gammopathy o

Under normal circumstances, serum creatinine values are determined by its metabolic generation from the muscle, renal excretion, and, to...

Kidney and renal pelvis cancer is the twelfth leading cause of cancer death in the United States (1). Renal cell carcinoma (RCC) accounts...