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Revealing the Unseen: Overlooked Causes of Pseudohyponatremia
One of the challenging cases in nephrology is managing a patient with severe hyponatremia, where each decision seems precarious. Overcorrecting sodium levels increases the risk of osmotic demyelination, while undercorrection leaves patients susceptible to complications. Nephrologists thread the needle carefully, focusing on avoiding overcorrection, typically aiming for a 24-hour correction rate below 6 to 8 mEq/L, or even lower at 4-6 mEq/L in patients with alcoholism, liver

Viresh Mohanlal, MD
Apr 105 min read


Interpreting Hypocitraturia: An Etiology First Approach
As a nephrologist, I frequently see patients with kidney stones, and one finding that appears with striking regularity on metabolic evaluations is hypocitraturia, defined as urine citrate <320 mg/day. In large-scale urine studies, hypocitraturia is now the third most common metabolic abnormality in stone formers, surpassed only by high urine calcium (>250mg/day) and low urine volume (< 2 L/day), significant risk factors for kidney stone formation (1). Over the past two decade

Viresh Mohanlal, MD
Nov 11, 20254 min read


Hyponatremia Due to Reset Osmostat: Uncovering the Clues
Hyponatremia, a condition affecting 1 in 3 hospitalized adult patients, is a prevalent and significant electrolyte abnormality (1). It is...

Viresh Mohanlal, MD
Apr 24, 20254 min read


Familial Hypocalciuric Hypercalcemia vs Primary Hyperparathyroidism: Deciphering the Differences
Primary hyperparathyroidism (PHPT) is a relatively common disorder affecting 85 per 100,000 men, with three times higher prevalence in...

Viresh Mohanlal, MD
Jun 21, 20243 min read


Idiopathic Hypercalcemia: Looking Beyond the Obvious
Primary hyperparathyroidism (PHPT) is the most common cause of parathyroid mediated hypercalcemia (high normal or high PTH) while...

Viresh Mohanlal, MD
May 31, 20243 min read
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